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Rare! To Provide A Safe Basis For The Application Of UVC-LED To The Human Body, Japan's Mie University Has Done Such An Experiment

Feb 14, 2022

D'aimsigh foireann taighde ó Ollscoil Mie sa tSeapáin gur féidir suthanna luath-iasc zebra (suthanna roinnt uaireanta tar éis toirchithe) a ionradáil go sábháilte le 278 nm UVC.


Úsáidtear LEDanna UVC timpeall 260nm le haghaidh steiriliú mar go gcothaíonn siad agus go díghníomhaíonn siad damáiste DNA ó bhaictéir agus víris. Díríonn an chuid is mó den taighde reatha ar éifeacht UVC le tonnfhaid faoi bhun 240nm (207nm, 222nm, 233nm) ar an choróinvíreas nua a mharú. Mar sin féin, is beag staidéar atá ar thocsaineacht, sábháilteacht agus freagairt orgánach d'ionradaíocht UVC timpeall 280 nm.

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Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.


After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.


Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².


The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.


Soláthraíonn torthaí taighde an ábhair seo bonn eolaíoch do shábháilteacht UVC-LED a chuirtear i bhfeidhm ar an gcorp daonna. Ag an am céanna, fuair an fhoireann taighde go bhfuil UVC oiriúnach do dhíghalrú baictéir agus víris lena n-áirítear an choróinvíreas, chomh maith le díghalrú sa dobharshaothrú.


"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.


Tá baint mhór ag teicneolaíocht GMKJ LED le foinsí solais sláintiúla agus cliste, ag soláthar an mhargaidh le raon iomlán de tháirgí agus réitigh UVA UVB UVC LED, infridhearg IR LED VCSEL, agus tá na céadta comhpháirtithe ardchaighdeáin intíre agus eachtrannacha ann. margaí chun úsáid na teicneolaíochta solais a chur chun cinn i gcomhpháirt chun saol sláintiúil agus cliste a chruthú. cúis.